Fixing Proteomics Campaign

Fixing Proteomics Campaign - help proteomics deliver its promise to aid successful drug discovery research Send to a colleagueNotify me when this site is updated

Experimental design for Proteomics, Step 1



Have you heard the story about Fahrenheit and the cow?

There is an urban myth why the inventor Fahrenheit ended up defining normal human body temperature as 98.6ºF rather than 100ºF as he wanted. To calibrate and check his thermometer he used a cow as standard to measure body temperature. He measured the temperature of the same cow many times and thought he had a reliable measurement. BUT the cow had a cold so he ended up with a number that translated to under 100ºF when he produced his final scale.

It doesn't matter how many times we take a measurement or to what accuracy, if we haven't used a good standard or controlled for biological variability within our experiment design we won't get a biologically relevant, reliable outcome.


This video includes narration

Next - Experimental design for Proteomics Step 2
Practical advice - 4-steps to Fixing Proteomics

Have you heard the story about Fahrenheit and the cow?